Masked antisense: a molecular configuration for discriminating similar RNA targets
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چکیده
منابع مشابه
Masked antisense: a molecular configuration for discriminating similar RNA targets.
Antisense technology has great potential for the control of RNA expression, but there remain few successful applications of the technology. Expressed antisense RNA can effectively down-regulate expression of a gene over long periods, but cannot differentiate partly identical sequences, such as the mRNA of fusion genes or those with point mutants. We have designed a structured form of expressed ...
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ژورنال
عنوان ژورنال: EMBO reports
سال: 2000
ISSN: 1469-221X,1469-3178
DOI: 10.1093/embo-reports/kvd003